James Cameron warned others against visiting the Titanic wreckage in a resurfaced interview, dubbing it 'one of the most unforgiving places on earth'.
The Oscar-winning director has made a total of 33 dives to the bottom of the Atlantic Ocean to see the ship's watery gravesite.
As per the New York Times, the Academy Award-winning director said: "It’s not like you can call up AAA to come get you."
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He added: "You’re going into one of the most unforgiving places on earth."
Cameron was even tucked away inside a submersible vessel at bottom of the North Atlantic on September 11 2001.
When he and his colleagues resurfaced, they had no idea that the new American nightmare was being faced miles away.
But, despite visiting the wreckage dozens of times, Cameron had warned others about exploring the great deep.
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Cameron's words have a new, eerie significance as experts reveal the five souls missing on OceanGate's missing Titan vessel, which disappeared on Sunday, now have about a ‘one per cent chance of survival’.
A huge search and rescue mission is currently underway to find the vanished submarine, which has five passengers on board: Hamish Harding; Paul-Henri Nargeolet; Shahzada Dawood and his son Sulaiman; and OceanGate CEO Stockton Rush.
Search teams are in a race against time to find the tiny submersible craft, which is said to have only around 96 hours worth of air inside, with reports the oxygen is due to run out at 12pm BST on Thursday, 22 June.
It is also feared that the submersible may be hard to find as the wreckage site sits on the ocean floor at a depth of around 12,500 feet (3,800 meters), meaning that it is difficult to access, even with sophisticated submersibles.
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Titanic expert Parks Stephenson, who worked with director James Cameron on his Oscar-winning disaster movie, has said he feels ‘concerned’ for those aboard as the search continues.
Stephenson, who travelled to the 1912 shipwreck with Cameron while working as a technical advisor on the film wrote on Facebook: “No matter what you may read in the coming hours, all that is truly known at this time is that communications with the submersible have been lost and that is unusual enough to warrant the most serious consideration.
“I am most concerned about the souls aboard, whose identities have not yet been made public.”
In another post, he confirmed he would be ‘declining all interview requests’, adding: “This is an evolving situation and I want to be respectful to everyone who might be affected by what has the potential to be a major tragedy. Likewise, I will not engage in comments to my posts regarding this subject.
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“Please keep the well being of all those potentially affected in your thoughts. They wouldn’t be out there if it wasn’t for the public demand for information regarding this wreck.”
James Cameron is yet to comment on the missing submersible.