Tom Sizemore, known for roles in Saving Private Ryan and Natural Born Killers, has died at the age of 61.
The US actor was placed in a coma after suffering a brain aneurysm and collapsing at his Los Angeles home on February 18.
His manager Charles Lago confirmed that Sizemore had died in his sleep on Friday at a hospital in Burbank, California.
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Lago said: "I am very saddened by the loss of not only a client but a great friend and mentor of almost 15 years.
"Tom was one of the most sincere, kind and generous human beings I have had the pleasure of knowing.
"His courage and determination through adversity was always an inspiration to me.
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"The past couple of years were great for him and he was getting his life back to a great place.
"He loved his sons and his family.
"I will miss my friend Tom Sizemore greatly.
"The Sizemore family has been comforted by the hundreds of messages of support and love shown to their son, brother and father.
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"They are asking for privacy during this difficult time and I am asking for those wishes to please be respected."
Prior to his death, his family said they were 'now deciding end-of-life matters'.
His brother Paul said: "I am deeply saddened by the loss of my big brother Tom. He was larger than life. He has influenced my life more than anyone I know.
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"He was talented, loving, giving and could keep you entertained endlessly with his wit and storytelling ability."
Paying tribute to the late actor, Licence to Kill and The Goonies actor Robert Davi highlighted Sizemore's 'struggle with addiction'.
He tweeted: "His family has my prayers - Tom and I were friends I knew of his suffering & his struggle with addiction - he was a terrific talent - Many families suffer from the heartbreak and tragedy of this disease and we do not do enough!!"
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Sizemore was praised for his portrayal of professional thief Michael Cheritto in the heist film Heat, written and directed by Michael Mann and starring the legendary Al Pacino and Robert De Niro.
As well as movies, he also made a contribution to the popular video game Grand Theft Auto: Vice City voicing mob boss Sonny Forelli.
Sizemore is survived by his 17-year-old twin sons, Jayden and Jagger, and his brother Paul, all of whom were by his side when he died.
Topics: Celebrity, Film and TV