The filmmaker, who has visited the shipwreck dozens of times himself, noted some stark similarities to the 1912 disaster.
Everyone on board the missing Titanic sub are believed to be dead, according to OceanGate.
The Coast Guard delivered the devastating news in a press conference
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OceanGate has issued a statement saying they believe everyone on board the Titan submersible to be 'lost'
Paul-Henri Nargeolet's daughter has spoken out after the longtime researcher of the Titanic wreck went missing.
The Coast Guard confirmed debris had been found in the search area
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A huge search and rescue operation is still ongoing for the missing Titan submarine
The sounds were just 'background ocean noise', according to the US Coast Guard
The coast guard shared the news after the estimated remaining amount of oxygen ran out
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The OceanGate sub originally set off on Sunday morning, with 96 hours worth of air to complete the exploratory dive of the Titanic.
OceanGate CEO Stockton Rush previously claimed Boeing and the University of Washington were involved
The episode originally aired in 2006, with The Simpsons seemingly predicting the missing OceanGate sub.
The OceanGate sub had been equipped with 96 hours worth of oxygen, before it disappeared on Sunday during a trip to the Titanic wreck.
He has previously voyaged to the Titanic wreck in a sub, having also found himself in grave danger at the time
The CEO of OceanGate, Stockton Rush, has a strange connection to the Titanic vessel
A US-based cable news network has come under fire for their 'insensitive' on-screen countdown timer as hope wanes for those lost of the sub.
The US Coast Guard revealed seven new vessels are racing to the search site as rescue teams run out of time to rescue those missing.
The confusing image left many people wondering what they were looking at as the search for the vanished vessel continues.
He made 33 dives to the ship's watery gravesite to film his Oscar-winning classic.
The OceanGate CEO was on board his submarine when it went missing beneath the sea
Five crew members are on board the Titanic submersible that has gone missing in the Atlantic Ocean.
The vessel had around 96-hours oxygen supply when it went missing
A former US Navy commander has said the crew are battling against the odds